Synthetic lethality cancer:Unleashing the Power of Synthetic Lethality
Unleashing the Power of Synthetic Lethality
由YDu著作·2023·被引用1次—Syntheticlethalityhasemergedasapromisingapproachtoaugmentthesensitivityofcancercellstochemotherapyagents.Syntheticlethality( ...。其他文章還包含有:「Definitionofsyntheticlethality」、「Syntheticlethalityandcancer」、「Complexsyntheticlethalityincancer」、「Thepowerandthepromiseofsyntheticlethalityforclinical...」、「NewHorizonsofSyntheticLethalityinCancer」、「Synthet...
查看更多 離開網站Definition of synthetic lethality
https://www.cancer.gov
Describes a situation in which mutations (changes) in two genes together result in cell death, but a mutation in either gene alone does not. Cancer cells that only have one mutated gene in a specific pair of genes can depend on the normal partner gene for
Synthetic lethality and cancer
https://www.nature.com
Synthetic lethality is a simple genetic concept that continues to have a major impact on cancer research. Synthetic lethal interaction data from ...
Complex synthetic lethality in cancer
https://www.nature.com
The concept of synthetic lethality has been widely applied to identify therapeutic targets in cancer, with varying degrees of success.
The power and the promise of synthetic lethality for clinical ...
https://www.sciencedirect.com
Synthetic lethality is a phenomenon wherein the simultaneous deficiency of two or more genes results in cell death, while the deficiency of any individual gene ...
New Horizons of Synthetic Lethality in Cancer
https://pubs.acs.org
This Perspective focuses on the most recent progress in synthetic lethal targets and their inhibitors, within and beyond the DNA damage response ...
Synthetic Lethality in Cancer Therapeutics
https://aacrjournals.org
AbstractSynthetic lethality (SL) provides a conceptual framework for tackling targets that are not classically “druggable,” including loss-of-function.
Synthetic lethality and cancer therapy
https://pubmed.ncbi.nlm.nih.go
We discuss the biological rationale for BRCA-PARP synthetic lethality, how the synthetic lethal approach is being assessed in the clinic, and how mechanisms of ...
Synthetic lethality
https://en.wikipedia.org
Synthetic lethality is defined as a type of genetic interaction where the combination of two genetic events results in cell death or death of an organism.
Advances in synthetic lethality for cancer therapy
https://jhoonline.biomedcentra
Synthetic lethality is a concept in genetics that have a significant impact on cancer study. The concept of synthetic lethality opens a new path ...