Synthetic lethality as an engine for cancer drug t：The power and the promise of synthetic lethality for clinical ...
The power and the promise of synthetic lethality for clinical ...
由QWLiu著作·2024—Inrecentyears,syntheticlethalityhasemergedasasignificanttopicinthefieldoftargetedcancertherapy,withcertaindrugsbasedonthisconcept ...。其他文章還包含有：「Syntheticlethalityasanengineforcancerdrugtarget...」、「What'snextforthesyntheticlethalitydrugdiscoveryengine?」、「[PDF]Syntheticlethalityasanengineforcancerdrugtarget...」、「NewHorizonsofSyntheticLethalityinCancer」、...
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Synthetic lethality as an engine for cancer drug target ...
https://pubmed.ncbi.nlm.nih.go
The first wave of genetically targeted therapies for cancer focused on drugging gene products that are recurrently mutated in specific cancer types.
What's next for the synthetic lethality drug discovery engine?
https://www.nature.com
As a surge of cancer drugs with new synthetic lethality targets enter the clinic, the opportunities and challenges of the underlying ...
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[PDF] Synthetic lethality as an engine for cancer drug target ...
https://www.semanticscholar.or
A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1. T. OikeH. Ogiwara +12 authors. T.
New Horizons of Synthetic Lethality in Cancer
https://pubs.acs.org
... T-cell lymphoma due to a lack of efficacy. The drug is now being ... Synthetic lethality as an engine for cancer drug target discovery.
Synthetic Lethality
https://www.gsk.com
Synthetic lethality can be applied in drug discovery to develop medicines that target specific genetic mutations expressed only in cancer cells, ...