Insulin resistance mechanism:Mechanisms of Insulin Action and Insulin Resistance

Mechanisms of Insulin Action and Insulin Resistance

Mechanisms of Insulin Action and Insulin Resistance

由MCPetersen著作·2018·被引用2602次—Inthisreview,boththephysiologyofinsulinactionandthepathophysiologyofinsulinresistancearedescribed,focusingonthreekeyinsulintargettissues.。其他文章還包含有:「InsulinResistance」、「Molecularandmetabolicmechanismsofinsulinresistance...」、「Thecrucialroleandmechanismofinsulinresistancein...」、「MechanismsforInsulinResistance」、「Trendsininsulinresistance」...

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Insulin resistance
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Insulin Resistance
Insulin Resistance

https://www.ncbi.nlm.nih.gov

Evidence shows insulin resistance is preceding and central to the development of T2DM and is mainly driven by ectopic fat accumulation in tissues. Moreover, ...

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Molecular and metabolic mechanisms of insulin resistance ...
Molecular and metabolic mechanisms of insulin resistance ...

https://www.nature.com

is caused by several factors, including direct deleterious effects of excess lipids and other ...

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The crucial role and mechanism of insulin resistance in ...
The crucial role and mechanism of insulin resistance in ...

https://www.frontiersin.org

Mechanistically explained, magnesium is a cofactor in the downstream action of the insulin cascade. Low magnesium ion levels lead to defective tyrosine kinase ...

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Mechanisms for Insulin Resistance
Mechanisms for Insulin Resistance

https://www.cell.com

Insulin activates the insulin receptor (IR) tyrosine kinase, which subsequently tyrosine phosphorylates IRS1 and 2. Through a set of ...

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Trends in insulin resistance
Trends in insulin resistance

https://www.nature.com

Insulin resistance (IR) is a disordered biological response for insulin stimulation through the disruption of different molecular pathways in target tissues.

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Mechanisms of inflammatory responses and development ...
Mechanisms of inflammatory responses and development ...

https://jbiomedsci.biomedcentr

Chronic inflammation plays a crucial role in variety of insulin resistant states [86, 87] in which various signaling pathways are activated that ...

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Insulin resistance
Insulin resistance

https://en.wikipedia.org

Insulin resistance (IR) is a pathological condition in which cells in insulin-sensitive tissues in the body fail to respond normally to the hormone insulin ...