T cell receptor structure:Structural understanding of T cell receptor triggering
Structural understanding of T cell receptor triggering
由XXu著作·2020·被引用56次—Here,wereviewTCRstructuralstudies,inparticular,antigen-inducedconformationalchangesontheextracellular,transmembraneandintracellulardomains.。其他文章還包含有:「Immunesystem-TCells」、「StructuralBiologyoftheT」、「StructuresofhumanγδTcellreceptor–CD3complex」、「Tcellreceptorsoverview」、「T」、「ThestructuralbasisofT」、「ThestructuralbasisofT」
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T-cell receptors consist of two polypeptide chains. The most common type of receptor is called alpha-beta because it is composed of two different chains, one ...
Structural Biology of the T
https://www.ncbi.nlm.nih.gov
(A) The TCR-CD3 complex is composed of four dimeric modules: TCRαβ (or γδ), CD3δε, CD3γε, and ζζ, which associate through intramembrane contacts to form the ...
Structures of human γδ T cell receptor–CD3 complex
https://www.nature.com
The Vγ5Vδ1 TCR–CD3 complex displays a dimeric assembly, comprising two protomers nestled back-to-back through their ECDs, with each MPD and TMD ...
T cell receptors overview
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The TCR, a defining structure of T cells, is a transmembrane heterodimer consisting of either an alpha and beta chain or delta and gamma chain linked by a ...
T
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The TCR is composed of two different protein chains (that is, it is a heterodimer). In humans, in 95% of T cells the TCR consists of an alpha (α) chain and a ...
The structural basis of T
https://www.jbc.org
The T-cell receptor (TCR)–CD3 complex is composed of a diverse αβ TCR heterodimer noncovalently associated with the invariant CD3 dimers CD3ϵγ, ...
The structural basis of T
https://www.ncbi.nlm.nih.gov
The T-cell receptor (TCR)–CD3 complex is composed of a diverse αβ TCR heterodimer noncovalently associated with the invariant CD3 dimers CD3ϵγ, CD3ϵδ, and CD3ζζ. The TCR mediates recognition of antigenic peptides bound to MHC molecules (pMHC), whereas the