t-cell receptor rearrangement：TCR gene rearrangements
TCR gene rearrangements
Definition of T
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Testing for these gene changes can tell whether large numbers of T cells with a certain T-cell receptor are being made. This may be a sign of T-cell lymphoma or ...
Mechanics of T cell receptor gene rearrangement
https://www.ncbi.nlm.nih.gov
TCR genes are assembled through V(D)J recombination, a site specific recombination process directed by the lymphoid-specific recombinase (RAG).
T Cell Receptor Gene Rearrangement Lineage Analysis ...
https://rupress.org
At the TCR-β loci of both chromosomes, a mature T cell may have up to three different DJ-β rearrangements in addition to its functional VDJ-β rearrangement.
T
https://www.sciencedirect.com
Functional immunoglobulin or T cell receptor gene rearrangements can help to assign a given cell to a stage of B or T cell development. These recombinations ...
T
https://www.testing.com
T-cell receptor gene rearrangement testing detects characteristic changes in specific genes in T-cells to help diagnose a T-cell lymphoma.
T
https://www.ncbi.nlm.nih.gov
The T-cell receptor gene segments rearrange during T-cell development to form complete V-domain exons (Fig. 4.12). T-cell receptor gene rearrangement takes ...
T
https://jamanetwork.com
T-cell receptor (TCR) gene rearrangement is a marker of clonality and may be used to detect early progression in the blood. ... This gene ...