spindle cell tumor differential diagnosis：Spindle cell lesions

INTRODUCTION

Spindle cell lesions of head and neck include a diverse group of clinically and biologically heterogeneous lesions. Some are malignant while many others are benign or simply reactive in nature. There is a diagnostic challenge to the oral pathologists to differentiate dizzying array of spindle cell lesions from other similar microscopic simulates ranging all the way from reactive to malignant and very aggressive.[1] More recently, a simple working type classification was proposed By the author Shamim 2013 for the spindle cell neoplasms of the oral cavity on the basis of predominance of spindle cells in the histopathology of the lesions of the oral cavity.[2] This article aims to review the spindle cell neoplasms of the oral cavity with emphasis on immunohistochemical markers. Including neural, myofibroblastic, muscle, fibroblastic, vascular, epithelial, odontogenic, and miscellaneous tumors.

NEURAL TUMORS

Th...