Bardoxolone methyl:FDA Rejects Bardoxolone Methyl For Chronic Kidney ...

FDA Rejects Bardoxolone Methyl For Chronic Kidney ...

FDA Rejects Bardoxolone Methyl For Chronic Kidney ...

2022年2月28日—ThecompleteresponseletterfromtheFDAcitedalackofeffectivenessinslowingthelossofkidneyfunctioninpatientswithAlportsyndrome.。其他文章還包含有:「Bardoxolonemethyl」、「Bardoxolonemethyl(CDDO」、「Bardoxolonemethyl(RTA402,甲基巴多索隆)」、「BardoxoloneMethyl」、「Bardoxolonemethylanalogattenuatesproteinuria」、「BardoxoloneMethylandKidneyFunctioninCKDwithType...」、「BardoxoloneMet...

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Bardoxolone methyl
Bardoxolone methyl

https://en.wikipedia.org

Bardoxolone methyl is an experimental and orally-bioavailable semi-synthetic triterpenoid, based on the scaffold of the natural product oleanolic acid.

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Bardoxolone methyl (CDDO
Bardoxolone methyl (CDDO

https://www.ncbi.nlm.nih.gov

As a multifunctional agent, CDDO-Me has improved the renal function in patients with chronic kidney disease associated with type 2 diabetes.

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Bardoxolone methyl (RTA 402,甲基巴多索隆)
Bardoxolone methyl (RTA 402,甲基巴多索隆)

https://www.medchemexpress.cn

Bardoxolone methyl (NSC 713200; RTA 402; CDDO Methyl ester) 是一种合成的三萜类化合物,具有潜在的抗肿瘤和抗炎活性,作为Nrf2 通路的激活剂和NF-κB 途径的抑制剂。

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Bardoxolone Methyl
Bardoxolone Methyl

https://www.sciencedirect.com

Bardoxolone methyl is a semisynthetic triterpene, which promotes antioxidant response and inhibits pro-inflammatory signals through activating nuclear factor ...

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Bardoxolone methyl analog attenuates proteinuria
Bardoxolone methyl analog attenuates proteinuria

https://pubmed.ncbi.nlm.nih.go

Multiple clinical studies have shown that bardoxolone methyl, a potent activator of nuclear factor erythroid 2-related factor 2 (Nrf2), is effective in ...

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Bardoxolone Methyl and Kidney Function in CKD with Type ...
Bardoxolone Methyl and Kidney Function in CKD with Type ...

https://www.nejm.org

Bardoxolone methyl, an oral antioxidant inflammation modulator, has shown efficacy in patients with CKD and type 2 diabetes in short-term ...

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Bardoxolone Methyl in Type 2 Diabetes and Stage 4 ...
Bardoxolone Methyl in Type 2 Diabetes and Stage 4 ...

https://www.nejm.org

Among patients with type 2 diabetes mellitus and stage 4 chronic kidney disease, bardoxolone methyl did not reduce the risk of ESRD or death ...

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Bardoxolone methyl: Uses
Bardoxolone methyl: Uses

https://go.drugbank.com

It is a novel targeted cancer therapy with a unique mechanism of action. It exploits fundamental physiological differences between cancerous and ...