htra1 genentech：Phase 1 Study of the Anti
Phase 1 Study of the Anti
由AMKhanani著作·2021·被引用21次—FHTR2163,anovelFabdirectedagainstHtrA1,waswelltoleratedwithnoDLTsor...5Genentech,Inc.,SouthSanFrancisco,CA,USA.。其他文章還包含有：「AllostericinhibitionofHTRA1activitybyaconformational...」、「Developmentofatherapeuticanti」、「EfficacyandSafetyofAnti–HighTemperatureRequirementA1...」、「OurPipeline」
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Allosteric inhibition of HTRA1 activity by a conformational ...
https://www.ncbi.nlm.nih.gov
HTRA1 is a secreted protease composed of an N-terminal IGFBP-domain, a Kazal-like domain, a central trypsin-like serine protease domain and a C- ...
Development of a therapeutic anti
https://www.pnas.org
Anti-HtrA1 Fab15H6.v4.D221 is also called FHTR2163 or RO7171009 and was supplied by Genentech. The study consists of a SAD stage with doses ...
Efficacy and Safety of Anti–High Temperature Requirement A1 ...
https://medically.gene.com
Aug 24 / Roche and Genentech. Efficacy and Safety of Anti–High Temperature Requirement A1 (Anti-HTRA1) Fab in Geographic Atrophy Secondary to AMD: GAllego ...
Our Pipeline
https://www.gene.com
Our Research and Early Development pipeline has over 30 new molecular entities (NMEs) in active clinical development.