Synthetic lethality:Synthetic Lethality
Synthetic Lethality
Syntheticlethalityisdefinedasthesituationwhenmutationineitheroftwogenesindividuallyhasnoeffect,butcombiningthemutationsleadstodeath.The ...。其他文章還包含有:「Advancesinsyntheticlethalityforcancertherapy」、「Developmentofsyntheticlethalityincancer」、「Syntheticlethality」、「Syntheticlethalityandcancer」、「Syntheticlethalityasanengineforcancerdrugtarget...」、「SyntheticLethalityinCancerT...
查看更多 離開網站Advances in synthetic lethality for cancer therapy
https://jhoonline.biomedcentra
Synthetic lethality is a phenomenon whereby the concurrent disruption of multiple genes results in cell death, while a disruption in an ...
Development of synthetic lethality in cancer
https://www.nature.com
Synthetic lethality provides a new approach for the treatment of mutated genes that were previously considered unable to be targeted in ...
Synthetic lethality
https://en.wikipedia.org
Synthetic lethality and cancer
https://www.nature.com
Synthetic lethality is a simple genetic concept that continues to have a major impact on cancer research. Synthetic lethal interaction data from ...
Synthetic lethality as an engine for cancer drug target ...
https://www.nature.com
The classic definition of synthetic lethality is cell autonomous, but a synthetic lethal approach can be adapted to identify druggable targets ...
Synthetic Lethality in Cancer Therapeutics
https://www.ncbi.nlm.nih.gov
A) Synthetic lethality is defined by cellular or organismal lethality caused by combined alterations of gene pairs that are otherwise ...
Synthetic lethality
https://pubmed.ncbi.nlm.nih.go
Precision oncology has made significant advances, mainly by targeting actionable mutations in cancer driver genes. Aiming to expand treatment ...
Synthetic lethality
https://www.ncbi.nlm.nih.gov
Synthetic lethality occurs when the simultaneous perturbation of two genes results in cellular or organismal death. Synthetic lethality also ...
The Concept of Synthetic Lethality in the Context ...
https://www.nature.com
Synthetic lethal interactions have most commonly been described for loss-of-function alleles, but can also involve gain-of-function alleles. For example, gene B ...