Sequencing technologies the next-generation：Next

5.1.1. Microbiome ResearchGiven the ubiquitous nature of microbes, their symbiotic, pathogenic, and commensal characteristics are of importance to humans by forming a highly functioning ecosystem. The microbiome community became an obligatory factor in our survival through evolution [165[1]]. However, a close monitoring and comprehensive understanding of the host–microbiome and microbiome–intercommunity interactions are vital to healthy survival. The approaches include pathogen surveillance, functional dysbiosis, and therapeutic potential. Metagenomic studies have linked the gut microbiome to disorders affecting mental health [166[2]], autoimmune diseases (rheumatoid arthritis) [167[3]], and metabolic disorders (diabetes and obesity) [168[4]], thus instrumental in evaluating the functional potential of the microbiome. This opens doors for more therapeutic approaches and options. Designing targeted panels to pick up mutations (aiding in antibiotic resistance tracking) or identifying t...