CRISPR-Cas9 CAR-T cell therapy:Engineering the next

Engineering the next

Engineering the next

由ADimitri著作·2022·被引用132次—CRISPR/Cas9-mediatedcytokinemodulationpotentiatesCART-cellfunctionandreducestoxicity.Geneticstrategiestomodulatecytokinesignaling ...。其他文章還包含有:「AdeepinsightintoCRISPRCas9applicationinCAR」、「CRISPRCAR」、「CRISPRexpandsCARTcellpossibilities」、「CRISPRCas9encouragedCAR」、「CRISPRCas9」、「Immuno」、「NoveltyinimprovementofCARTcell」、「Revolutionizi...

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GillmoreJD,MaitlandML,LebwohlD.CRISPR-Cas9InVivoGeneEditingforTransthyretinAmyloidosis.ReplyNEnglJMed.2021;385:1722–3.PubMed[1] GoogleScholar[2] FrangoulH,HoTW,CorbaciogluS.CRISPR-Cas9GeneEditingforSickleCellDiseaseandbeta-Thalassemia.Reply.NEnglJMed.2021;384:e91.Article[3] PubMed[4] GoogleScholar[5] StadtmauerEA,FraiettaJA,DavisMM,CohenAD,WeberKL,LancasterE,ManganPA,KulikovskayaI,GuptaM,ChenF,etal.CRISPR-engineeredTcellsinpatientswithrefractorycancer.Science.2020;367:eaba7365.Article[6] CAS...

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A deep insight into CRISPRCas9 application in CAR
A deep insight into CRISPRCas9 application in CAR

https://stemcellres.biomedcent

investigated the use of CRISPR/Cas9 gene editing in CD19-specific CAR-T cells by transduction with a lentiviral construct including a guide RNA ...

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CRISPR CAR
CRISPR CAR

https://www.synthego.com

By combining CAR-T therapy with CRISPR-Cas9 gene editing technology, scientists are now hopeful that they will be able to cure cancer for good.

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CRISPR expands CAR T cell possibilities
CRISPR expands CAR T cell possibilities

https://www.nature.com

CRISPR-Cas9 is effective at generating small mutations by creating targeted double-stranded DNA (dsDNA) breaks that are then repaired by the cell's non- ...

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CRISPRCas9 encouraged CAR
CRISPRCas9 encouraged CAR

https://www.sciencedirect.com

CRISPR/Cas9 used in CAR-T cell formation, helps in knock-out [14] of all the toxicity related genes and also knocking-in of desirable cytokine genes to boost ...

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CRISPRCas9
CRISPRCas9

https://www.ncbi.nlm.nih.gov

Recently, CRISPR/Cas9 technology has provided an effective approach to promoting the proliferation and persistence of CAR-T cells in the body.

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Immuno
Immuno

https://crisprtx.com

We are developing a portfolio of chimeric antigen receptor (CAR) T cell product candidates using our gene editing technology. CAR T cell therapy is a form of ...

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Novelty in improvement of CAR T cell
Novelty in improvement of CAR T cell

https://www.htct.com.br

Figure 3. Improvement of CAR-T cell therapy by CRISPR/Cas9 technology: three major aspects of the CRISPR/Cas9 application in the CAR-T cell therapy ...

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Revolutionizing cancer treatment
Revolutionizing cancer treatment

https://www.frontiersin.org

The combination of CRISPR/Cas9 technology and CAR-T cell therapy may promote the development of this therapy and provide more effective and personalized ...